Arsenal Boss, Arsene Wenger
Arsenal boss Arsene Wenger says it is a "massive wake-up call" that no English clubs have reached the quarter-finals of the Champions League.
Bayern Munich's victory over the Gunners on the away goals rule on Wednesday means England will not have a team in the last eight for the first time since the 1995-96 season.
"It's a massive disappointment for English football," said Wenger.
"We accept the rest of European football has caught back on us."
Reigning Premier League champions Manchester City finished bottom of their group, which featured Real Madrid, Borussia Dortmund and Ajax, after failing to win any of their six matches, reports the BBC.
Chelsea, who defeated Bayern Munich to win the Champions League last season, also failed to advance past the group stage, while Manchester United went out to Real Madrid in the last 16 stage.
Arsenal, trailing 3-1 from the first leg, overcame Bayern Munich 2-0 in Germany on Wednesday but missed out on a place in the quarter-finals on the away goals rule.
"If you think we had Manchester City and United, Chelsea and Arsenal all out by the quarter-final - it's a long time since that happened," added Wenger.
"We have to take that into consideration in the way we think about the future of the Premier League."
However, Bayern boss Jupp Heynckes has tipped Premier League clubs to be back in the later stages of the competition again next season.
"I think comparisons like this don't bring much, we have had German teams knocked out early in previous years," said Heynckes.
"I think Manchester United were unlucky to get knocked out and Arsenal showed what a quality team they are.
"You get cycles like that in football, I think the English teams will be back next year."
Arsenal's exit means they face an eighth season without silverware.
The Gunners produced a gutsy performance but left themselves with too much to do, despite goals by Olivier Giroud and Laurent Koscielny.
"I'm very proud of the performance of the team, but very disappointed for everybody who follows Arsenal that we couldn't get that third goal," added Wenger.
"I think there was room to score, and when you look at the game you have many regrets for our first game."