Ajax score against Man City
Manchester City's hopes of qualifying for the Champions League knockout stage suffered another crushing blow with a deserved loss to Ajax in Amsterdam, while Arsenal also suffered a shock 2-0 home loss to German side, Schalke 04.
In Amsterdam, both clubs were desperate for a victory to kick-start their Group F campaigns and Samir Nasri slotted City ahead against the run of play.
But Siem de Jong equalised with a low finish just before half-time and Niklas Moisander headed Ajax into the lead.
Christian Eriksen sealed the win with a strike deflected in by Gael Clichy.
It is a result that leaves City bottom of the table with one point from three games and three matches remaining.
They host Ajax on 6 November and Real Madrid on 21 November before finishing at Borussia Dortmund on 4 December.
Dortmund lead the way on seven points, one clear of Real and three above Ajax. The top two advance to the last 16.
And at the Emirates, Arsenal were handed their first defeat in the Champions League this season by Schalke's Dutch pair of Klaas-Jan Huntelaar and Ibrahim Afellay.
Huntelaar, who had two other good chances, grabbed the first 15 minutes from time when he fired low past Gunners goalkeeper Vito Mannone.
And with four minutes remaining, Afellay made it 2-0 when he swept in Jefferson Farfan's cross.
Arsenal's best chance fell to lone forward Gervinho, who fired wide.
Another shock occurred in Germany where Dortmund came from a goal down to beat Jose Mourinho’s Real Madrid 2-1.
In other games, Zenit beat Anderlecht 1-0, PSG won away at Dinamo Zagreb 2-0, FC Porto beat Dynamo Kiev 3 – 2,
Malaga continued to compound AC Milan’s woes with a 1 - 0 win while Greek side, Olympiakos came from behind in France to beat Montpellier 1 - 2
UEFA LEAGUE RESULTS
Zenit St P'sbg 1 - 0 Anderlecht
Ajax 3 - 1 Man City
Arsenal 0 - 2 Schalke 04
Borussia Dortmund 2 - 1 Real Madrid
Din Zagreb 0 - 2 Paris SG
FC Porto 3 - 2 Dynamo Kiev
Malaga 1 - 0 AC Milan
Montpellier 1 - 2 Olympiakos