World number three, Rafael Nadal has pulled out of the US Open after failing to recover from a knee injury.
The 26-year-old's last action was at Wimbledon, in June, when he was beaten in the second round by Lukas Rosol, ranked 100 in the world, reports the BBC.
He was then forced to pull out of the London 2012 Olympics with the injury, which has since failed to clear up.
"I am very sad to announce that I am still not ready to play," said Nadal in a statement.
He added: "I am sorry since I always found great crowds and great support, but I have to continue with my recuperation and preparation to be ready to play in the right conditions.
"I want to say hi and thanks to all the fans, in particular to the New Yorkers. I'll miss you all this year at the Open!"
The US Open, which Nadal won in 2010, starts on 27 August with Andy Murray looking to win his first Grand Slam.