Arsenal stars, Jack Wilshire (L) and Theo Walcott
Deadline day signing Nacho Monreal is available to make his Arsenal debut and could be thrust straight in at left-back after Kieran Gibbs suffered a thigh injury against Liverpool which is set to keep him sidelined for several weeks.
Midfielder Mikel Arteta could return to the squad following a spell out with a calf strain, but Francis Coquelin will not be considered as he is still recovering from a hamstring problem.
Thomas Vermaelen is also doubtful so there could be a start for Laurent Koscielny, as Arsenal seek an improvement on the defensive display against Liverpool, reports futaa.com.
Stoke manager Tony Pulis has no fresh injury concerns, although Marc Wilson remains a long-term absentee with a broken leg.
Rory Delap and Matthew Upson are unavailable after signing loan deals with Barnsley and Brighton respectively.
Peter Crouch and Kenwyne Jones ended up staying at the club despite speculation about moves elsewhere, and are competing for a starting place alongside Jon Walters.
Brek Shea's work permit hearing was successful on Thursday but he will need to build up his fitness before being given a Premier League bow.